Tetrahydrofuran → 4-(1-Hydroxycyclobutyl)benzonitrile
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1.[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14].[CH2:15]1[CH2:16][CH2:17][CH2:18][O:19]1>>[c:2]1([C:18]2([OH:19])[CH2:15][CH2:16][CH2:17]2)[cH:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1Participants
4
Sources & evidence
- ORD record
- ord-8abd2b0b4a9c41409390870f464964d6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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