Sodium ion → 4-(3-Chloro-4-fluorophenyl)-tetrahydro-pyran-4-carbonitrile
Reaction equation
[CH3:21][N:22]1[CH2:23][CH2:24][CH2:25][C:26]1=[O:27].[Cl:10][c:11]1[cH:12][c:13]([CH2:18][C:19]#[N:20])[cH:14][cH:15][c:16]1[F:17].[Cl:3][CH2:4][CH2:5][O:6][CH2:7][CH2:8][Cl:9].[H-:2].[Na+:1]>>[CH2:4]1[CH2:5][O:6][CH2:7][CH2:8][C:18]1([c:13]1[cH:12][c:11]([Cl:10])[c:16]([F:17])[cH:15][cH:14]1)[C:19]#[N:20]Participants
6
Sources & evidence
- ORD record
- ord-a5a1d61b9bfb4ed1951f82025aeb4bed
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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