Hydrochloric Acid → 1-Benzyl-4-methylamino-3,3-dimethylpiperidine

HRID 806179Notes

Reaction equation

HRID 806179 reaction equation
[C:22](#[N:23])[BH3-:24].[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[N:13]1[CH2:14][C:15]([CH3:20])([CH3:21])[C:16](=[O:19])[CH2:17][CH2:18]1.[CH3:26][OH:27].[CH3:4][NH2:5].[ClH:3].[K+:2].[Na+:25].[OH-:1]>>[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[N:13]1[CH2:14][C:15]([CH3:20])([CH3:21])[CH:16]([NH:23][CH3:22])[CH2:17][CH2:18]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 813Potassium CationHCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 6329MethylamineHCID 498716Cyano-borohydrideHCID 97944131-Benzyl-3,3-dimethylpiperidin-4-one

Product 1

HCID 222788881-Benzyl-4-methylamino-3,3-dimethylpiperidine

Sources & evidence

ORD record
ord-388226cce2f0403da240772b348a7b01
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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