Tetrahydrofuran → t-Butyl [2-(4-nitropyridine-2-carboxamido)ethyl]carbamate

HRID 806652Notes

Reaction equation

HRID 806652 reaction equation
[C:29]([n:30]1[cH:31][cH:32][n:33][cH:34]1)([n:35]1[cH:36][cH:37][n:38][cH:39]1)=[O:40].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][c:6]([C:10](=[O:11])[OH:12])[n:7][cH:8][cH:9]1.[NH2:13][CH2:14][CH2:15][NH:16][C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23].[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][c:6]([C:10](=[O:12])[NH:13][CH2:14][CH2:15][NH:16][C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[n:7][cH:8][cH:9]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 682631,1'-CarbonyldiimidazoleHCID 187201N-BOC-ethylenediamineHCID 27628254-Nitropicolinic Acid

Product 1

HCID 13800214t-Butyl [2-(4-nitropyridine-2-carboxamido)ethyl]carbamate

Sources & evidence

ORD record
ord-b84b9b8843e04917ba613ff7a516d7f5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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