Guaiacol → 1-Methoxy-2-(2,2,2-trifluoroethoxy)benzene

HRID 806732Notes

Reaction equation

HRID 806732 reaction equation
[C:10](=[O:11])([O-:12])[O-:13].[CH3:1][O:2][c:3]1[c:4]([OH:9])[cH:5][cH:6][cH:7][cH:8]1.[CH3:23][N:24]1[CH2:25][CH2:26][CH2:27][C:28]1=[O:29].[F:16][C:17]([CH2:18][I:19])([F:20])[F:21].[K+:14].[K+:15].[OH2:22]>>[CH3:1][O:2][c:3]1[c:4]([O:9][CH2:18][C:17]([F:16])([F:20])[F:21])[cH:5][cH:6][cH:7][cH:8]1

Participants

7

Reactant 6

HCID 460GuaiacolHCID 813Potassium Cation2×HCID 962WaterHCID 13387N-methyl-2-pyrrolidoneHCID 19660Carbonate IonHCID 677091,1,1-Trifluoro-2-iodoethane

Product 1

HCID 200943441-Methoxy-2-(2,2,2-trifluoroethoxy)benzene

Sources & evidence

ORD record
ord-05e7c987333842f481acc6d90213aa09
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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