Dimethylformamide → tert-Butyl 4-(5-nitropyridine-2-ylamino)piperidine-1-carboxylate

HRID 806742Notes

Reaction equation

HRID 806742 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1.[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH2:20][CH:21]([NH2:24])[CH2:22][CH2:23]1.[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:32][N:33]([CH3:34])[CH:35]=[O:36]>>[c:2]1([NH:24][CH:21]2[CH2:20][CH2:19][N:18]([C:16]([O:15][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:17])[CH2:23][CH2:22]2)[n:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 782402-Bromo-5-nitropyridineHCID 12682914-Amino-1-Boc-piperidine

Product 1

HCID 53255493tert-Butyl 4-(5-nitropyridine-2-ylamino)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-ad6c1b0493af4d43a6886fd0dacd19a8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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