Trifluoroacetic acid → 2-(5-Fluoro-2-methyl-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[NH:12][CH:11]([c:16]1[c:17]([CH3:23])[cH:18][cH:19][c:20]([F:22])[cH:21]1)[C:10]([CH3:24])([CH3:25])[CH:9]2[OH:26].[CH2:34]([SiH:35]([CH2:36][CH3:37])[CH2:38][CH3:39])[CH3:40].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[NH:12][CH:11]([c:16]1[c:17]([CH3:23])[cH:18][cH:19][c:20]([F:22])[cH:21]1)[C:10]([CH3:24])([CH3:25])[CH2:9]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-cee899603dbe48f0ad7a63aa24609d90
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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