1,2-Dichloroethane → 5-Cyclohex-1-enyl-3-[(1-formyl-piperidin-4-yl)-(trans-4-methyl-cyclohexanecarbonyl)-amino]-thiophene-2-carboxylic acid methyl ester

HRID 807369Notes

Reaction equation

HRID 807369 reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:26]2=[CH:27][CH2:28][CH2:29][CH2:30][CH2:31]2)[cH:8][c:9]1[N:10]([CH:11]1[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1)[C:17](=[O:18])[CH:19]1[CH2:20][CH2:21][CH:22]([CH3:25])[CH2:23][CH2:24]1.[CH:36](=[O:37])[O:38][CH2:39][CH3:40].[Cl:32][CH2:33][CH2:34][Cl:35]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:26]2=[CH:27][CH2:28][CH2:29][CH2:30][CH2:31]2)[cH:8][c:9]1[N:10]([CH:11]1[CH2:12][CH2:13][N:14]([CH:36]=[O:37])[CH2:15][CH2:16]1)[C:17](=[O:18])[CH:19]1[CH2:20][CH2:21][CH:22]([CH3:25])[CH2:23][CH2:24]1

Participants

4

Reactant 3

HCID 111,2-DichloroethaneHCID 8025Ethyl formateHCID 577953625-Cyclohex-1-enyl-3-[(trans-4-methyl-cyclohexanecarbonyl)-piperidin-4-yl-amino]-thiophene-2-carboxylic acid methyl ester

Product 1

HCID 577953895-Cyclohex-1-enyl-3-[(1-formyl-piperidin-4-yl)-(trans-4-methyl-cyclohexanecarbonyl)-amino]-thiophene-2-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-26f9cc9e082549ff87dc8eb98437b8b0
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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