Hydrochloric Acid → tert-Butyl 4-oxopiperidine-1-carboxylate

HRID 807385Notes

Reaction equation

HRID 807385 reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17]([O:18][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:19].[ClH:1].[NH:3]1[CH2:4][CH2:5][C:6](=[O:9])[CH2:7][CH2:8]1.[Na+:11].[OH-:10].[OH2:24].[OH2:2]>>[N:3]1([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH2:4][CH2:5][C:6](=[O:9])[CH2:7][CH2:8]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 962Water2×HCID 337214-PiperidoneHCID 10219638Carbonic acid, bis(1,1-dimethylethyl) ester

Product 1

HCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Sources & evidence

ORD record
ord-f562e9daf3154b32adbd8bf14b14d912
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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