Water → Benzofuran-5-yl-(3-ethoxy-4-methoxy-phenyl)-methanol

HRID 807427Notes

Reaction equation

HRID 807427 reaction equation
[Br:1][c:2]1[cH:3][c:4]([O:10][CH2:11][CH3:12])[c:5]([O:8][CH3:9])[cH:6][cH:7]1.[CH2:13]([Li:14])[CH2:15][CH2:16][CH3:17].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH:29]([OH:30])([CH3:31])[CH3:32].[OH2:38].[o:18]1[cH:19][cH:20][c:21]2[c:22]1[cH:23][cH:24][c:25]([CH:27]=[O:28])[cH:26]2>>[c:2]1([CH:27]([c:25]2[cH:24][cH:23][c:22]3[o:18][cH:19][cH:20][c:21]3[cH:26]2)[OH:28])[cH:3][c:4]([O:10][CH2:11][CH3:12])[c:5]([O:8][CH3:9])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 962WaterHCID 3776IsopropanolHCID 8028TetrahydrofuranHCID 27738751-Benzofuran-5-carbaldehydeHCID 217726904-Bromo-2-ethoxy-1-methoxybenzeneHCID 178418339Butyllithium

Product 1

HCID 68936547Benzofuran-5-yl-(3-ethoxy-4-methoxy-phenyl)-methanol

Sources & evidence

ORD record
ord-e531f6df1e75400eb60c8581572ac705
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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