Allyl bromide → 5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-(cyclopropylmethyl)-3-prop-2-enylpiperidin-2-one

HRID 808359Notes

Reaction equation

[CH2:26]([CH:27]=[CH2:28])[Br:29].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:30][Si:31]([N-:32][Si:33]([CH3:34])([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[CH2:9][CH2:10][C:11](=[O:25])[N:12]([CH2:21][CH:22]3[CH2:23][CH2:24]3)[CH:13]2[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:5][cH:6][cH:7]1.[Li+:39]>>[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[CH2:9][CH:10]([CH2:28][CH:27]=[CH2:26])[C:11](=[O:25])[N:12]([CH2:21][CH:22]3[CH2:23][CH2:24]3)[CH:13]2[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:5][cH:6][cH:7]1