Dimethylformamide → 3-Bromo-5-fluorobenzaldehyde

HRID 808729Notes

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([Br:9])[cH:5][c:6]([F:8])[cH:7]1.[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14].[CH3:15][N:16]([CH:17]=[O:18])[CH3:19].[O:20]1[CH2:21][CH2:22][CH2:23][CH2:24]1>>[c:2]1([CH:17]=[O:18])[cH:3][c:4]([Br:9])[cH:5][c:6]([F:8])[cH:7]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 8028Tetrahydrofuran

HCID 1370031,3-Dibromo-5-fluorobenzene

HCID 178418339Butyllithium

Product 1

HCID 219862463-Bromo-5-fluorobenzaldehyde

Sources & evidence

ORD record: ord-628aa208223e4b6db75a982b8f8e8c30
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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