Bromide ion → (6-Methanesulfonyl-1H-indol-3-yl)-(2,2,3,3-tetramethyl-cyclopropyl)-methanone

HRID 808911Notes

Reaction equation

HRID 808911 reaction equation
[Br-:14].[CH2:15]([Mg+:16])[CH3:17].[CH3:18][C:19]1([CH3:27])[CH:20]([C:24](=[O:25])[Cl:26])[C:21]1([CH3:22])[CH3:23].[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8]2[cH:9][cH:10][nH:11][c:12]2[cH:13]1.[Cl-:28].[Cl-:30].[Zn+2:29]>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8]2[c:9]([C:24]([CH:20]3[C:19]([CH3:18])([CH3:27])[C:21]3([CH3:22])[CH3:23])=[O:25])[cH:10][nH:11][c:12]2[cH:13]1

Participants

7

Reactant 6

HCID 259Bromide ionHCID 312Chloride2×HCID 32051Zinc(2+)HCID 27610676-methanesulfonyl-1H-indoleHCID 110410022,2,3,3-Tetramethylcyclopropane-1-carbonyl chlorideHCID 178461628HCID 178461628, compound

Product 1

HCID 24824474(6-Methanesulfonyl-1H-indol-3-yl)-(2,2,3,3-tetramethyl-cyclopropyl)-methanone

Sources & evidence

ORD record
ord-1f6dd560c39d41c9b01d34264ef05ef8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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