Sodium ion → 4-[4-[[4-[[4-(2-Diethoxyphosphorylethenyl)-1-phenylpyrazol-3-yl]oxymethyl]-2-methoxyphenoxy]methyl]-1,3-thiazol-2-yl]morpholine

HRID 809092Notes

Reaction equation

HRID 809092 reaction equation
[CH2:37]([P:38](=[O:39])([O:40][CH2:41][CH3:42])[O:43][CH2:44][CH3:45])[P:46]([O:47][CH2:48][CH3:49])([O:50][CH2:51][CH3:52])=[O:53].[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][O:7][c:8]2[n:9][n:10](-[c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)[cH:11][c:12]2[CH:13]=[O:14])[cH:21][cH:22][c:23]1[O:24][CH2:25][c:26]1[n:27][c:28]([N:31]2[CH2:32][CH2:33][O:34][CH2:35][CH2:36]2)[s:29][cH:30]1.[CH3:54][N:55]([CH3:56])[CH:57]=[O:58].[H-:59].[Na+:60].[OH2:61]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][O:7][c:8]2[n:9][n:10](-[c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)[cH:11][c:12]2[CH:13]=[CH:37][P:46]([O:47][CH2:48][CH3:49])([O:50][CH2:51][CH3:52])=[O:53])[cH:21][cH:22][c:23]1[O:24][CH2:25][c:26]1[n:27][c:28]([N:31]2[CH2:32][CH2:33][O:34][CH2:35][CH2:36]2)[s:29][cH:30]1

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 15455Tetraethyl methylenediphosphonateHCID 166653HydrideHCID 230765713-({3-methoxy-4-[(2-morpholin-4-yl-1,3-thiazol-4-yl)methoxy]benzyl}oxy)-1-phenyl-1H-pyrazole-4-carbaldehyde

Product 1

HCID 911116194-[4-[[4-[[4-(2-Diethoxyphosphorylethenyl)-1-phenylpyrazol-3-yl]oxymethyl]-2-methoxyphenoxy]methyl]-1,3-thiazol-2-yl]morpholine

Sources & evidence

ORD record
ord-6f3074394e324113915fcfaa2cdc71c3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…