4-Hydroxybenzoic Acid → Tert-butyl 4-{4-[(4-hydroxybenzoyl)amino]phenyl}piperazine-1-carboxylate

HRID 809108Notes

Reaction equation

HRID 809108 reaction equation
[CH3:31][N:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[O:38]=[CH:39][N:40]([CH3:41])[CH3:42].[OH:21][C:22](=[O:23])[c:24]1[cH:25][cH:26][c:27]([OH:28])[cH:29][cH:30]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1)[C:22](=[O:21])[c:24]1[cH:25][cH:26][c:27]([OH:28])[cH:29][cH:30]1

Participants

5

Reactant 4

HCID 1354-Hydroxybenzoic AcidHCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 11011301tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate

Product 1

HCID 54019812Tert-butyl 4-{4-[(4-hydroxybenzoyl)amino]phenyl}piperazine-1-carboxylate

Sources & evidence

ORD record
ord-94c882d20f5d448d980f256f232ce7dc
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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