Tetrahydrofuran → Methyl 4-(2-chloro-5-nitropyrimidin-4-yl)-3-methylmorpholine-3-carboxylate

HRID 810778Notes

Reaction equation

HRID 810778 reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:1][C:2]1([C:8](=[O:9])[O:10][CH3:11])[CH2:3][O:4][CH2:5][CH2:6][NH:7]1.[CH:23]([N:24]([CH:25]([CH3:26])[CH3:27])[CH2:28][CH3:29])([CH3:30])[CH3:31].[Cl:12][c:13]1[n:14][cH:15][c:16]([N+:20](=[O:21])[O-:22])[c:17]([Cl:19])[n:18]1>>[CH3:1][C:2]1([C:8](=[O:9])[O:10][CH3:11])[CH2:3][O:4][CH2:5][CH2:6][N:7]1[c:17]1[c:16]([N+:20](=[O:21])[O-:22])[cH:15][n:14][c:13]([Cl:12])[n:18]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 81531DiisopropylethylamineHCID 5212662,4-Dichloro-5-nitropyrimidineHCID 67268303Methyl 3-methylmorpholine-3-carboxylate

Product 1

HCID 78165341Methyl 4-(2-chloro-5-nitropyrimidin-4-yl)-3-methylmorpholine-3-carboxylate

Sources & evidence

ORD record
ord-c4b18ecbfd2f4e278100b7fa68bb3fba
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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