Sodium ion → 6-Bromo-3,4-dihydro-2H-isoquinolin-1-one

HRID 810962Notes

Reaction equation

HRID 810962 reaction equation
[Br:6][c:7]1[cH:8][c:9]2[c:13]([cH:14][cH:15]1)[C:12](=[O:16])[CH2:11][CH2:10]2.[CH3:1][S:2](=[O:3])(=[O:4])[OH:5].[Cl:23][CH2:24][Cl:25].[N-:18]=[N+:19]=[N-:20].[Na+:17].[Na+:22].[OH-:21]>>[Br:6][c:7]1[cH:8][c:9]2[c:13]([cH:14][cH:15]1)[C:12](=[O:16])[NH:18][CH2:11][CH2:10]2

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 961HydroxideHCID 6344DichloromethaneHCID 6395Methanesulfonic AcidHCID 33558AzideHCID 5206955-Bromo-1-indanone

Product 1

HCID 218654506-Bromo-3,4-dihydro-2H-isoquinolin-1-one

Sources & evidence

ORD record
ord-93aaac087ee24ae59fd61b5813e268b8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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