Dimethylformamide → Tert-butyl 4-(5-(5-(4-(difluoromethoxy)phenyl)pyrimidin-2-ylamino)nicotinoyl)piperazine-1-carboxylate

HRID 811231Notes

Reaction equation

[C:60](=[O:61])([O:62][C:63]([CH3:64])([CH3:65])[CH3:66])[N:67]1[CH2:68][CH2:69][NH:70][CH2:71][CH2:72]1.[CH:51]([N:52]([CH2:53][CH3:54])[CH:55]([CH3:56])[CH3:57])([CH3:58])[CH3:59].[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[cH:11][n:12][c:13]([NH:16][c:17]3[cH:18][n:19][cH:20][c:21]([C:22](=[O:23])[OH:24])[cH:25]3)[n:14][cH:15]2)[cH:8][cH:9]1)[F:26].[O:73]=[CH:74][N:75]([CH3:76])[CH3:77].[P-:27]([F:28])([F:29])([F:30])([F:31])([F:32])[F:33].[n:34]1([O:35][C:36]([N:37]([CH3:38])[CH3:39])=[N+:40]([CH3:41])[CH3:42])[c:43]2[n:44][cH:45][cH:46][cH:47][c:48]2[n:49][n:50]1>>[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[cH:11][n:12][c:13]([NH:16][c:17]3[cH:18][n:19][cH:20][c:21]([C:22](=[O:24])[N:70]4[CH2:69][CH2:68][N:67]([C:60](=[O:61])[O:62][C:63]([CH3:64])([CH3:65])[CH3:66])[CH2:72][CH2:71]4)[cH:25]3)[n:14][cH:15]2)[cH:8][cH:9]1)[F:26]