Hydrochloric Acid → Risperidal iMpurity B

HRID 811268Notes

Reaction equation

[CH3:34][CH2:35][OH:36].[ClH:31].[F:1][c:2]1[c:3]([C:4](=[O:5])[CH:6]2[CH2:7][CH2:8][N:9]([CH2:12][CH2:13][c:14]3[c:15]([CH3:25])[n:16][c:17]4[n:18]([c:19]3=[O:20])[CH2:21][CH2:22][CH2:23][CH2:24]4)[CH2:10][CH2:11]2)[cH:26][cH:27][c:28]([F:30])[cH:29]1.[K+:38].[NH2:32][OH:33].[OH-:37].[cH:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1>>[F:1][c:2]1[c:3]([C:4]([CH:6]2[CH2:7][CH2:8][N:9]([CH2:12][CH2:13][c:14]3[c:15]([CH3:25])[n:16][c:17]4[n:18]([c:19]3=[O:20])[CH2:21][CH2:22][CH2:23][CH2:24]4)[CH2:10][CH2:11]2)=[N:32][OH:33])[cH:26][cH:27][c:28]([F:30])[cH:29]1