Tetrahydrofuran → 3-(3-(4-(3-Ethynyl-benzyloxy)-benzyl)-isoxazol-5-yl)-pyridin-2,6-diamine

HRID 811300Notes

Reaction equation

[C:22](#[CH:23])[c:24]1[cH:25][c:26]([CH2:30][OH:31])[cH:27][cH:28][cH:29]1.[NH2:1][c:2]1[n:3][c:4]([NH2:21])[cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([OH:20])[cH:18][cH:19]2)[n:11][o:12]1.[O:51]=[C:52]([O:53][CH2:54][CH3:55])[N:56]=[N:57][C:58]([O:59][CH2:60][CH3:61])=[O:62].[O:63]1[CH2:64][CH2:65][CH2:66][CH2:67]1.[c:32]1([P:33]([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[cH:46][cH:47][cH:48][cH:49][cH:50]1>>[NH2:1][c:2]1[n:3][c:4]([NH2:21])[cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH2:30][c:26]3[cH:25][c:24]([C:22]#[CH:23])[cH:29][cH:28][cH:27]3)[cH:18][cH:19]2)[n:11][o:12]1