Water → 7-Bromo-8-methoxycarbonyl-1,3,3-trimethyl-3,4-dihydro-1H-quinoxalin-2-one

HRID 811435Notes

Reaction equation

HRID 811435 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([c:11]1[C:12](=[O:13])[O:14][CH3:15])[NH:9][C:8](=[O:16])[C:7]([CH3:17])([CH3:18])[NH:6]2.[CH3:19][I:20].[CH3:21][CH2:22][O:23][C:24](=[O:25])[CH3:26].[CH3:28][N:29]([CH3:30])[CH:31]=[O:32].[OH2:27]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([c:11]1[C:12](=[O:13])[O:14][CH3:15])[N:9]([CH3:21])[C:8](=[O:16])[C:7]([CH3:17])([CH3:18])[NH:6]2

Participants

6

Reactant 5

HCID 962WaterHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 8857Ethyl AcetateHCID 24780709Methyl 6-bromo-2,2-dimethyl-3-oxo-1,2,3,4-tetrahydroquinoxaline-5-carboxylate

Product 1

HCID 247809997-Bromo-8-methoxycarbonyl-1,3,3-trimethyl-3,4-dihydro-1H-quinoxalin-2-one

Sources & evidence

ORD record
ord-393c73705bde4314abaf9f3a97276216
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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