Dimethylformamide → 4-Chloro-7-(2-chloroethoxy)-6-methoxy-3-quinolinecarbonitrile

HRID 811500Notes

Reaction equation

HRID 811500 reaction equation
[CH2:31]([Cl:32])[Cl:33].[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[Cl:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([O:18][CH3:19])[cH:7][c:8]2[c:9]([OH:17])[c:10]([C:15]#[N:16])[cH:11][n:12][c:13]2[cH:14]1.[Cl:20][C:21]([C:22]([Cl:23])=[O:24])=[O:25]>>[Cl:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([O:18][CH3:19])[cH:7][c:8]2[c:9]([Cl:20])[c:10]([C:15]#[N:16])[cH:11][n:12][c:13]2[cH:14]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 178486762HCID 178486762, compound

Product 1

HCID 111092524-Chloro-7-(2-chloroethoxy)-6-methoxy-3-quinolinecarbonitrile

Sources & evidence

ORD record
ord-1c13e23e9f4041af9aa0eb23da890c9f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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