Ammonium → Ethyl 2-[(1,1'-biphenyl)-4-yl]-2-hydroxypropionate

HRID 811888Notes

Reaction equation

HRID 811888 reaction equation
[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:21][Mg+:22].[Cl-:23].[I-:20].[NH4+:24].[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([C:11](=[O:12])[C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:18][cH:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([C:11]([OH:12])([C:13](=[O:14])[O:15][CH2:16][CH3:17])[CH3:21])[cH:18][cH:19]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312ChlorideHCID 8028TetrahydrofuranHCID 30165Iodide IonHCID 80389Ethyl 4-phenylbenzoylformateHCID 178477777HCID 178477777, compound

Product 1

HCID 21184093Ethyl 2-[(1,1'-biphenyl)-4-yl]-2-hydroxypropionate

Sources & evidence

ORD record
ord-0f18d46e7ef14b6e9be3db4008edbce1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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