Hydrogen Bromide → 5'-Bromo-3,2'-difluorobiphenyl-2-carbonitrile
Reaction equation
[BrH:22].[CH2:23]1[O:24][CH2:25][CH2:26][O:27][CH2:28]1.[Cu:30][Br:31].[N:18]([O-:19])=[O:20].[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:17])[c:6](-[c:8]2[c:9]([C:15]#[N:16])[c:10]([F:14])[cH:11][cH:12][cH:13]2)[cH:7]1.[Na+:21].[OH2:29]>>[c:2]1([Br:22])[cH:3][cH:4][c:5]([F:17])[c:6](-[c:8]2[c:9]([C:15]#[N:16])[c:10]([F:14])[cH:11][cH:12][cH:13]2)[cH:7]1Participants
8
Sources & evidence
- ORD record
- ord-bea3af3cc1034e68a9832ecc063c82ce
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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