Hydrochloric Acid → Ethyl 3-{[(4-{[1-(5-methoxy-3-methyl-1-benzofuran-2-yl)-3-methylbutyl]amino}phenyl)carbonyl]amino}propanoate

HRID 812076Notes

Reaction equation

HRID 812076 reaction equation
[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[Cl:1][CH:2]([CH2:3][CH:4]([CH3:5])[CH3:6])[c:7]1[o:8][c:9]2[c:10]([c:11]1[CH3:12])[cH:13][c:14]([O:17][CH3:18])[cH:15][cH:16]2.[ClH:44].[I-:37].[NH2:19][c:20]1[cH:21][cH:22][c:23]([C:26](=[O:27])[NH:28][CH2:29][CH2:30][C:31](=[O:32])[O:33][CH2:34][CH3:35])[cH:24][cH:25]1.[Na+:36].[Na+:38].[Na+:39].[O-:40][C:41](=[O:42])[O-:43]>>[CH:2]([CH2:3][CH:4]([CH3:5])[CH3:6])([c:7]1[o:8][c:9]2[c:10]([c:11]1[CH3:12])[cH:13][c:14]([O:17][CH3:18])[cH:15][cH:16]2)[NH:19][c:20]1[cH:21][cH:22][c:23]([C:26](=[O:27])[NH:28][CH2:29][CH2:30][C:31](=[O:32])[O:33][CH2:34][CH3:35])[cH:24][cH:25]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 923Sodium ion3×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 30165Iodide IonHCID 12469762Ethyl 3-(4-aminobenzamido)propanoateHCID 667782182-(1-Chloro-3-methylbutyl)-5-methoxy-3-methyl-1-benzofuran

Product 1

HCID 66778503Ethyl 3-{[(4-{[1-(5-methoxy-3-methyl-1-benzofuran-2-yl)-3-methylbutyl]amino}phenyl)carbonyl]amino}propanoate

Sources & evidence

ORD record
ord-bf75d265bd9543558cda0a4c67650dc9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…