Potassium Cation → 2-(4-Trifluoromethylphenylamino)-3-methylbutanoic acid

HRID 813599Notes

Reaction equation

HRID 813599 reaction equation
[C:20](=[O:21])([O-:22])[O-:23].[CH3:28][C:29]([N:30]([CH3:31])[CH3:32])=[O:33].[Cu:26][I:27].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([I:9])[cH:7][cH:8]1)([F:10])[F:11].[K+:24].[K+:25].[NH2:12][CH:13]([CH:14]([CH3:15])[CH3:16])[C:17](=[O:18])[OH:19]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([NH:12][CH:13]([CH:14]([CH3:15])[CH3:16])[C:17](=[O:18])[OH:19])[cH:7][cH:8]1)([F:10])[F:11]

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 1182DL-valineHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 31374DimethylacetamideHCID 67993Benzene, 1-iodo-4-(trifluoromethyl)-

Product 1

HCID 133884532-(4-Trifluoromethylphenylamino)-3-methylbutanoic acid

Sources & evidence

ORD record
ord-bd1d803e9dc14b888969b63436a56ebf
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…