Dimethylformamide → N-(4-chlorophenyl)-N'-(2-(4-(5-methyl-3-oxo-1H-imidazo[1,5-c]imidazol-2(3H)-yl)-1-piperidinyl)-2-oxo-1-phenylethyl)urea

HRID 813911Notes

Reaction equation

HRID 813911 reaction equation
[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[Cl:27][c:28]1[cH:29][cH:30][c:31]([N:34]=[C:35]=[O:36])[cH:32][cH:33]1.[NH2:1][CH:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([N:11]2[C:12](=[O:20])[n:13]3[c:14]([cH:16][n:17][c:18]3[CH3:19])[CH2:15]2)[CH2:9][CH2:10]1)[c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1.[O:37]=[CH:38][N:39]([CH3:40])[CH3:41]>>[NH:1]([CH:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([N:11]2[C:12](=[O:20])[n:13]3[c:14]([cH:16][n:17][c:18]3[CH3:19])[CH2:15]2)[CH2:9][CH2:10]1)[c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[C:35]([NH:34][c:31]1[cH:30][cH:29][c:28]([Cl:27])[cH:33][cH:32]1)=[O:36]

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 76934-Chlorophenyl IsocyanateHCID 8857Ethyl AcetateHCID 231380962-(1-(2-amino-2-phenylacetyl)-4-piperidinyl)-5-methyl-1,2-dihydro-3H-imidazo[1,5-c]imidazol-3-one

Product 1

HCID 23138178N-(4-chlorophenyl)-N'-(2-(4-(5-methyl-3-oxo-1H-imidazo[1,5-c]imidazol-2(3H)-yl)-1-piperidinyl)-2-oxo-1-phenylethyl)urea

Sources & evidence

ORD record
ord-c1ecf17d07804926a2a9270111736048
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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