Methanol → Cis-4-(7-{[2-({4-[(diethoxyphosphoryl)methyl]-2-methoxyphenyl}amino)-5-(trifluoromethyl)pyrimidin-4-yl]amino}-2-methyl-1-oxo-2,3-dihydro-1H-isoindol-4-yl)cyclohexanecarboxylic acid

HRID 814218Notes

Reaction equation

[CH2:1]([CH3:2])[O:3][P:4](=[O:5])([O:6][CH2:7][CH3:8])[CH2:9][c:10]1[cH:11][c:12]([O:50][CH3:51])[c:13]([NH:16][c:17]2[n:18][cH:19][c:20]([C:46]([F:47])([F:48])[F:49])[c:21]([NH:23][c:24]3[cH:25][cH:26][c:27]([CH:35]4[CH2:36][CH2:37][CH:38]([C:41](=[O:42])[O:43][CH2:44][CH3:45])[CH2:39][CH2:40]4)[c:28]4[c:32]3[C:31](=[O:33])[N:30]([CH3:34])[CH2:29]4)[n:22]2)[cH:14][cH:15]1.[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[CH3:57][OH:58].[Li+:59].[OH-:60].[OH2:61]>>[CH2:1]([CH3:2])[O:3][P:4](=[O:5])([O:6][CH2:7][CH3:8])[CH2:9][c:10]1[cH:11][c:12]([O:50][CH3:51])[c:13]([NH:16][c:17]2[n:18][cH:19][c:20]([C:46]([F:47])([F:48])[F:49])[c:21]([NH:23][c:24]3[cH:25][cH:26][c:27]([CH:35]4[CH2:36][CH2:37][CH:38]([C:41](=[O:42])[OH:43])[CH2:39][CH2:40]4)[c:28]4[c:32]3[C:31](=[O:33])[N:30]([CH3:34])[CH2:29]4)[n:22]2)[cH:14][cH:15]1