Dichloromethane → benzyl N-(2-ethoxy-5-oxooxolan-3-yl)carbamate

HRID 814245Notes

Reaction equation

HRID 814245 reaction equation
[C:1]([O:2][C:6]([CH2:7][CH:8]([CH:9]([O:10][CH2:11][CH3:12])[O:13][CH2:3][CH3:4])[NH:16][C:17](=[O:18])[O:19][CH2:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)=[O:27])([CH3:5])([CH3:14])[CH3:15].[CH3:28][O:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[Cl:43][CH2:44][Cl:45].[F:36][C:37]([F:38])([F:39])[C:40]([OH:41])=[O:42]>>[C:6]1(=[O:27])[CH2:7][CH:8]([NH:16][C:17](=[O:18])[O:19][CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[CH:9]([O:10][CH2:11][CH3:12])[O:13]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 7519AnisoleHCID 694647453-Benzyloxycarbonylamino-4,4-diethoxy-butyric acid tert-butyl ester

Product 1

HCID 23577000benzyl N-(2-ethoxy-5-oxooxolan-3-yl)carbamate

Sources & evidence

ORD record
ord-83ab55c7907e41069e49c14509ac1ce7
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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