Trifluoroacetic acid → 3-Methyl-5-[4-(methylamino)pent-1-enyl]pyridin-2-amine

HRID 814799Notes

Reaction equation

[CH3:30][O:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[CH3:8][N:9]([CH:10]([CH3:11])[CH2:12][CH:13]=[CH:14][c:15]1[cH:16][n:17][c:18]([NH2:22])[c:19]([CH3:21])[cH:20]1)[C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[CH3:8][NH:9][CH:10]([CH3:11])[CH2:12][CH:13]=[CH:14][c:15]1[cH:16][n:17][c:18]([NH2:22])[c:19]([CH3:21])[cH:20]1

Participants

Reactant 3

HCID 6422Trifluoroacetic acid

HCID 7519Anisole

HCID 54405412tert-butyl N-[5-(6-amino-5-methyl-3-pyridinyl)pent-4-en-2-yl]-N-methylcarbamate

Product 1

HCID 544645073-Methyl-5-[4-(methylamino)pent-1-enyl]pyridin-2-amine

Sources & evidence

ORD record: ord-81315ec004854e5ca8d0b846e60d4f1f
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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