Dimethylamine → tert-butyl 3-[3-chloro-N-[3-(dimethylamino)propyl]-4-fluoroanilino]pyrrolidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([N:13]([CH2:14][CH2:15][CH2:16][Cl:17])[c:18]2[cH:19][c:20]([Cl:25])[c:21]([F:24])[cH:22][cH:23]2)[CH2:11][CH2:12]1.[CH3:26][NH:27][CH3:28].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[I-:30].[Na+:29].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36].[OH2:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([N:13]([CH2:14][CH2:15][CH2:16][N:27]([CH3:26])[CH3:28])[c:18]2[cH:19][c:20]([Cl:25])[c:21]([F:24])[cH:22][cH:23]2)[CH2:11][CH2:12]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-93e5f7e4619d4b63b14b3ff5bda69a6a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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