HRID814891

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6344

Dichloromethane

CH2Cl2

HCID8258

2-Methyl-3-butyn-2-ol

C5H8O

HCID8471

Triethylamine

C6H15N

HCID11776

Triphenylphosphine

C18H15P

2 次

HCID24290

未命名化合物

HCID24350

Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

CuI

HCID1516508

2-Amino-5-bromo-3-iodopyridine

C5H4BrIN2

PRODUCTS

生成物

HCID58129303

4-(2-Amino-5-bromo-3-pyridinyl)-2-methyl-3-butyn-2-ol

C10H11BrN2O

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-593368dc319549b5818c3208941aef5d
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH3:10][CH2:11][N:12]([CH2:13][CH3:14])[CH2:15][CH3:16].[CH3:17][C:18]([C:19]#[CH:20])([OH:21])[CH3:22].[Cl:23][CH2:24][Cl:25].[Cu:67][I:68].[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:9])[cH:6][c:7]1[I:8].[Pd:26]([Cl:27])[Cl:28].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1>>[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:9])[cH:6][c:7]1[C:20]#[C:19][C:18]([CH3:17])([OH:21])[CH3:22]