Potassium Cation → 5-(4-tert-Butylphenyl)-1-(4-isopropoxyphenyl)indole-2-carboxylic acid ethyl ester
Reaction equation
[Br:39][c:40]1[cH:41][cH:42][c:43]([O:46][CH:47]([CH3:48])[CH3:49])[cH:44][cH:45]1.[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[nH:7][c:8]2[cH:9][cH:10][c:11](-[c:15]3[cH:16][cH:17][c:18]([C:21]([CH3:22])([CH3:23])[CH3:24])[cH:19][cH:20]3)[cH:12][c:13]2[cH:14]1.[CH3:33][NH:34][CH2:35][CH2:36][NH:37][CH3:38].[CH3:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1.[CH3:57][CH2:58][O:59][C:60]([CH3:61])=[O:62].[Cu:63][I:64].[K+:30].[K+:31].[K+:32].[P:25]([O-:26])([O-:27])([O-:28])=[O:29]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7](-[c:40]2[cH:41][cH:42][c:43]([O:46][CH:47]([CH3:48])[CH3:49])[cH:44][cH:45]2)[c:8]2[cH:9][cH:10][c:11](-[c:15]3[cH:16][cH:17][c:18]([C:21]([CH3:22])([CH3:23])[CH3:24])[cH:19][cH:20]3)[cH:12][c:13]2[cH:14]1Participants
9
Reactant 8
HCID 813Potassium Cation3×
HCID 1061Phosphate
HCID 1140Toluene
HCID 8070N,N'-Dimethylethylenediamine
HCID 8857Ethyl Acetate
HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)
HCID 2280881-Bromo-4-(propan-2-yloxy)benzene
HCID 68475095Ethyl 5-(4-(tert-butyl)phenyl)-1H-indole-2-carboxylateProduct 1
Sources & evidence
- ORD record
- ord-26a6405a8bbb4b469190f2374d1cc9a7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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