Tetrahydrofuran → 2-(Aminomethyl)-4-chlorophenol

HRID 814979Notes

Reaction equation

[Al+3:2].[Cl:7][c:8]1[cH:9][cH:10][c:11]([OH:17])[c:12]([C:13](=[O:14])[NH2:15])[cH:16]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[O:18]1[CH2:19][CH2:20][CH2:21][CH2:22]1>>[Cl:7][c:8]1[cH:9][cH:10][c:11]([OH:17])[c:12]([CH2:13][NH2:15])[cH:16]1

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 3480945-Chloro-2-hydroxybenzamide

Product 1

HCID 2308442-(Aminomethyl)-4-chlorophenol

Sources & evidence

ORD record: ord-e9aac1cc292746d29b5e9ff544265efc
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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