Bicarbonate Ion → N-(3,5-Dichlorobenzyl)-1-(4-fluorophenyl)methanamine

HRID 815077Notes

Reaction equation

HRID 815077 reaction equation
[C:20]([O:21][BH-:22]([O:23][C:24](=[O:25])[CH3:26])[O:27][C:28](=[O:29])[CH3:30])(=[O:31])[CH3:32].[CH3:39][CH:40]([OH:41])[CH3:42].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[Cl:1][c:2]1[cH:3][c:4]([CH:5]=[O:6])[cH:7][c:8]([Cl:10])[cH:9]1.[Cl:43][CH2:44][Cl:45].[F:11][c:12]1[cH:13][cH:14][c:15]([CH2:16][NH2:17])[cH:18][cH:19]1.[Na+:33].[Na+:38].[O-:34][C:35]([OH:36])=[O:37]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][NH:17][CH2:16][c:15]2[cH:14][cH:13][c:12]([F:11])[cH:19][cH:18]2)[cH:7][c:8]([Cl:10])[cH:9]1

Participants

9

Reactant 8

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 3776IsopropanolHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 357463,5-DichlorobenzaldehydeHCID 673264-FluorobenzylamineHCID 2724942Triacetoxyborohydride

Product 1

HCID 58531427N-(3,5-Dichlorobenzyl)-1-(4-fluorophenyl)methanamine

Sources & evidence

ORD record
ord-286edc8117054df5890b034d3ec946f9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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