Ethylene Glycol → 2-(5-Bromo-2-fluorophenyl)-1,3-dioxolane

HRID 815094Notes

Reaction equation

HRID 815094 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:10])[c:6]([CH:7]=[O:8])[cH:9]1.[CH3:12][c:13]1[cH:14][cH:15][c:16]([S:17]([OH:18])(=[O:19])=[O:20])[cH:21][cH:22]1.[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[CH3:34][CH2:35][O:36][C:37]([CH3:38])=[O:39].[OH2:11].[OH:23][CH2:24][CH2:25][OH:26]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:10])[c:6]([CH:7]2[O:8][CH2:25][CH2:24][O:23]2)[cH:9]1

Participants

7

Reactant 6

HCID 174Ethylene GlycolHCID 962WaterHCID 1140TolueneHCID 6101p-Toluenesulfonic acidHCID 8857Ethyl AcetateHCID 7363275-Bromo-2-fluorobenzaldehyde

Product 1

HCID 184555852-(5-Bromo-2-fluorophenyl)-1,3-dioxolane

Sources & evidence

ORD record
ord-ae251e7c4db24a558851d361f98bcefa
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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