Tetrahydrofuran → (5RS)-3-(4-Bromophenyl)-5-isoxazol-3-yloxymethyl-4,5-dihydro-isoxazole

HRID 815259Notes

Reaction equation

HRID 815259 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:9][O:10][CH:11]([CH2:13][OH:14])[CH2:12]2)[cH:6][cH:7]1.[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1.[OH:34][c:35]1[n:36][o:37][cH:38][cH:39]1.[c:15]1([P:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2=[N:9][O:10][CH:11]([CH2:13][O:14][c:35]3[n:36][o:37][cH:38][cH:39]3)[CH2:12]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 15888252[3-(4-Bromophenyl)-4,5-dihydro-1,2-oxazol-5-yl]methanolHCID 178516613HCID 178516613, compound

Product 1

HCID 22022984(5RS)-3-(4-Bromophenyl)-5-isoxazol-3-yloxymethyl-4,5-dihydro-isoxazole

Sources & evidence

ORD record
ord-13ca651ae754434d97b281e61a96e162
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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