Tetrahydrofuran → 6-Fluoro-2-[(2-fluoro-4-iodophenyl)amino]nicotinic acid
Reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:11][Si:12]([N-:13][Si:14]([CH3:15])([CH3:16])[CH3:17])([CH3:18])[CH3:19].[F:1][c:2]1[c:3]([NH2:4])[cH:5][cH:6][c:7]([I:9])[cH:8]1.[F:20][c:21]1[c:22]([C:23](=[O:24])[OH:25])[cH:26][cH:27][c:28]([F:30])[n:29]1.[Li+:10]>>[F:1][c:2]1[c:3]([NH:4][c:21]2[c:22]([C:23](=[O:24])[OH:25])[cH:26][cH:27][c:28]([F:30])[n:29]2)[cH:5][cH:6][c:7]([I:9])[cH:8]1Participants
6
Sources & evidence
- ORD record
- ord-2a9cc83d476645dc825a2f8da1c47301
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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