Phenol → (5-Methyl-furan-2-ylmethyl)-(5-phenoxymethyl-quinolin-2-yl)-amine

HRID 816326Notes

Reaction equation

HRID 816326 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([CH2:7][NH:8][c:9]2[n:10][c:11]3[cH:12][cH:13][cH:14][c:15]([CH2:19][OH:20])[c:16]3[cH:17][cH:18]2)[o:6]1.[O:47]=[C:48]([O:49][CH:50]([CH3:51])[CH3:52])[N:53]=[N:54][C:55]([O:56][CH:57]([CH3:58])[CH3:59])=[O:60].[O:61]1[CH2:62][CH2:63][CH2:64][CH2:65]1.[OH:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1.[c:28]1([P:29]([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[cH:42][cH:43][cH:44][cH:45][cH:46]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5]([CH2:7][NH:8][c:9]2[n:10][c:11]3[cH:12][cH:13][cH:14][c:15]([CH2:19][O:20][c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[c:16]3[cH:17][cH:18]2)[o:6]1

Participants

6

Reactant 5

HCID 996PhenolHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 44218152{2-[(5-Methyl-furan-2-ylmethyl)-amino]-quinolin-5-yl}-methanol

Product 1

HCID 68436647(5-Methyl-furan-2-ylmethyl)-(5-phenoxymethyl-quinolin-2-yl)-amine

Sources & evidence

ORD record
ord-0ce6d7845ccc42b6a5e25bf4caa9dd6e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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