HRID817176

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID9886

Hexafluorophosphate ion

F6P-

HCID81531

Diisopropylethylamine

C8H19N

结构：CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C

HCID124335

Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium

C12H22N6OP+

HCID256208

5-Methylnicotinic acid

C7H7NO2

HCID22091429

tert-Butyl 4-amino-4-cyanopiperidine-1-carboxylate

C11H19N3O2

PRODUCTS

生成物

结构：Cc1cncc(C(=O)NC2(C#N)CCN(C(=O)OC(C)(C)C)CC2)c1

HCID67401046

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-74098f8e37aa40679888cea29331682a
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14]#[N:15])([NH2:16])[CH2:12][CH2:13]1.[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH2:59]([N:60]([CH:61]([CH3:62])[CH3:63])[CH:64]([CH3:65])[CH3:66])[CH3:67].[CH3:44][c:45]1[cH:46][n:47][cH:48][c:49]([C:50](=[O:51])[OH:52])[cH:53]1.[P-:17]([F:18])([F:19])([F:20])([F:21])([F:22])[F:23].[n:24]1([O:25][P+:26]([N:27]([CH3:28])[CH3:29])([N:30]([CH3:31])[CH3:32])[N:33]([CH3:34])[CH3:35])[c:36]2[cH:37][cH:38][cH:39][cH:40][c:41]2[n:42][n:43]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14]#[N:15])([NH:16][C:50]([c:49]2[cH:48][n:47][cH:46][c:45]([CH3:44])[cH:53]2)=[O:51])[CH2:12][CH2:13]1