Tetrahydrofuran → 4-Cyano-4-[(5-methyl-pyridine-3-carbonyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester

HRID 817176Notes

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14]#[N:15])([NH2:16])[CH2:12][CH2:13]1.[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH2:59]([N:60]([CH:61]([CH3:62])[CH3:63])[CH:64]([CH3:65])[CH3:66])[CH3:67].[CH3:44][c:45]1[cH:46][n:47][cH:48][c:49]([C:50](=[O:51])[OH:52])[cH:53]1.[P-:17]([F:18])([F:19])([F:20])([F:21])([F:22])[F:23].[n:24]1([O:25][P+:26]([N:27]([CH3:28])[CH3:29])([N:30]([CH3:31])[CH3:32])[N:33]([CH3:34])[CH3:35])[c:36]2[cH:37][cH:38][cH:39][cH:40][c:41]2[n:42][n:43]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14]#[N:15])([NH:16][C:50]([c:49]2[cH:48][n:47][cH:46][c:45]([CH3:44])[cH:53]2)=[O:51])[CH2:12][CH2:13]1