Methanol → 6-chloro-4'-[5-chloro-2-(2-hydroxycarbonyl-2-methyl-propoxy)-phenyl]-2'-(5-fluoro-2-methylphenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

HRID 817423Notizen

Reaktionsgleichung

[CH3:45][OH:46].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:34]2[c:35]([CH3:41])[cH:36][cH:37][c:38]([F:40])[cH:39]2)[NH:13][C:14](=[O:33])[CH2:15][CH:16]1[c:17]1[c:18]([O:24][CH2:25][C:26]([CH3:27])([CH3:28])[C:29](=[O:30])[O:31][CH3:32])[cH:19][cH:20][c:21]([Cl:23])[cH:22]1.[Na+:43].[OH-:42].[OH2:44]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:34]2[c:35]([CH3:41])[cH:36][cH:37][c:38]([F:40])[cH:39]2)[NH:13][C:14](=[O:33])[CH2:15][CH:16]1[c:17]1[c:18]([O:24][CH2:25][C:26]([CH3:27])([CH3:28])[C:29](=[O:30])[OH:31])[cH:19][cH:20][c:21]([Cl:23])[cH:22]1