Hydrochloric Acid → [1-(4-Methoxy-2,6-dimethyl-phenylsulfonyl)-piperidin-2-yl]-methanol

HRID 817652Notes

Reaction equation

HRID 817652 reaction equation
[CH3:16][O:17][c:18]1[cH:19][c:20]([CH3:29])[c:21]([S:25](=[O:26])(=[O:27])[Cl:28])[c:22]([CH3:24])[cH:23]1.[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[Cl:31][CH2:32][Cl:33].[ClH:30].[NH:1]1[CH:2]([CH2:7][OH:8])[CH2:3][CH2:4][CH2:5][CH2:6]1>>[N:1]1([S:25]([c:21]2[c:20]([CH3:29])[cH:19][c:18]([O:17][CH3:16])[cH:23][c:22]2[CH3:24])(=[O:26])=[O:27])[CH:2]([CH2:7][OH:8])[CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 8471TriethylamineHCID 94263Piperidin-2-ylmethanolHCID 159174964-Methoxy-2,6-dimethylbenzene-1-sulfonyl chloride

Product 1

HCID 43574491[1-(4-Methoxy-2,6-dimethyl-phenylsulfonyl)-piperidin-2-yl]-methanol

Sources & evidence

ORD record
ord-3417f58656024d33b977256a3511f25d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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