Chloride → 1-[2-(3,7-dimethylocta-2,6-dienoxy)-3,5-dihydro-2H-1,4-benzothiazepin-4-yl]prop-2-en-1-one

HRID 817877Notes

Reaction equation

HRID 817877 reaction equation
[C:1]([CH:2]=[CH2:3])(=[O:4])[N:5]1[CH2:6][CH:7]([Cl:16])[S:8][c:9]2[c:10]([cH:12][cH:13][cH:14][cH:15]2)[CH2:11]1.[CH3:17][C:18]([CH3:19])=[CH:20][CH2:21][CH2:22][C:23]([CH3:24])=[CH:25][CH2:26][OH:27].[Cl-:28].[Cl-:30].[Zn+2:29]>>[C:1]([CH:2]=[CH2:3])(=[O:4])[N:5]1[CH2:6][CH:7]([O:27][CH2:26][CH:25]=[C:23]([CH2:22][CH2:21][CH:20]=[C:18]([CH3:17])[CH3:19])[CH3:24])[S:8][c:9]2[c:10]([cH:12][cH:13][cH:14][cH:15]2)[CH2:11]1

Participants

5

Reactant 4

HCID 312Chloride2×HCID 44583,7-Dimethyl-2,6-octadienolHCID 32051Zinc(2+)HCID 152916584-Acryloyl-2-chloro-2,3,4,5-tetrahydro-1,4-benzothiazepine

Product 1

HCID 543188421-[2-(3,7-dimethylocta-2,6-dienoxy)-3,5-dihydro-2H-1,4-benzothiazepin-4-yl]prop-2-en-1-one

Sources & evidence

ORD record
ord-41b67ef95e3249bf81df706cb2054c05
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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