Methanol → 2-(2-Chloro-6-methyl-benzoylamino)-indane-2-carboxylic acid ethyl ester

HRID 818088Notes

Reaction equation

HRID 818088 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([NH2:15])[CH2:7][c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2[CH2:14]1.[CH3:36][OH:37].[CH3:38][N:39]([CH3:40])[c:41]1[cH:42][cH:43][n:44][cH:45][cH:46]1.[CH:16]([N:17]([CH2:18][CH3:19])[CH:20]([CH3:21])[CH3:22])([CH3:23])[CH3:24].[Cl:25][c:26]1[c:27]([C:28](=[O:29])[Cl:30])[c:31]([CH3:35])[cH:32][cH:33][cH:34]1.[Cl:47][CH2:48][Cl:49]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([NH:15][C:28]([c:27]2[c:26]([Cl:25])[cH:34][cH:33][cH:32][c:31]2[CH3:35])=[O:29])[CH2:7][c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2[CH2:14]1

Participants

7

Reactant 6

HCID 887MethanolHCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 81531DiisopropylethylamineHCID 10921653Ethyl 2-amino-2,3-dihydro-1H-indene-2-carboxylateHCID 223820402-Chloro-6-methylbenzoyl chloride

Product 1

HCID 593142712-(2-Chloro-6-methyl-benzoylamino)-indane-2-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-36564b377a704839961f497d3345e7fd
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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