Water → 6-(2,4-Difluorophenyl)-5-(3-isopropyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)imidazo[2,1-b]thiazole

HRID 818313Notes

Reaction equation

[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[F:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[s:12][cH:13][cH:14][n:15]3[c:16]2[I:17])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[I:18][c:19]1[cH:20][cH:21][c:22]2[n:23]([n:24]1)[c:25]([CH:28]([CH3:29])[CH3:30])[n:26][n:27]2.[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[OH2:41].[cH:42]1[cH:43][cH:44][c:45]([P:46]([Pd:47]([P:48]([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)([c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)([P:67]([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)[P:86]([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)([c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)([c:105]2[cH:106][cH:107][cH:108][cH:109][cH:110]2)[c:111]2[cH:112][cH:113][cH:114][cH:115][cH:116]2)[cH:117][cH:118]1>>[F:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[s:12][cH:13][cH:14][n:15]3[c:16]2-[c:19]2[cH:20][cH:21][c:22]3[n:23]([n:24]2)[c:25]([CH:28]([CH3:29])[CH3:30])[n:26][n:27]3)[cH:4][cH:5][c:6]([F:8])[cH:7]1