Dimethylformamide → [6-Chloro-4-(7-chloro-imidazo[1,2-a]pyridin-3-yl)-pyridin-2-yl]-methyl-amine

HRID 818449Notes

Reaction equation

HRID 818449 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:19][NH2:20].[Cl:1][c:2]1[cH:3][c:4]2[n:5]([cH:6][cH:7]1)[c:8](-[c:11]1[cH:12][c:13]([Cl:18])[n:14][c:15]([Cl:17])[cH:16]1)[cH:9][n:10]2.[Cl:32][CH2:33][Cl:34].[Cs+:25].[Cs+:26].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31]>>[Cl:1][c:2]1[cH:3][c:4]2[n:5]([cH:6][cH:7]1)[c:8](-[c:11]1[cH:12][c:13]([NH:20][CH3:19])[n:14][c:15]([Cl:17])[cH:16]1)[cH:9][n:10]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 6329MethylamineHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 866443467-Chloro-3-(2,6-dichloro-pyridin-4-yl)-imidazo[1,2-a]pyridine

Product 1

HCID 86644347[6-Chloro-4-(7-chloro-imidazo[1,2-a]pyridin-3-yl)-pyridin-2-yl]-methyl-amine

Sources & evidence

ORD record
ord-f1f0eab416a0440fa0e658b66f57f77a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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