Ammonium → N-(2-amino-7'-methoxyspiro[5H-1,3-oxazole-4,9'-xanthene]-2'-yl)-5-chloropyridine-2-carboxamide
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([O:21][CH3:22])[cH:13][c:14]1[C:15]21[N:16]=[C:17]([NH2:20])[O:18][CH2:19]1.[C:33](=[O:34])([O-:35])[O-:36].[CH3:39][NH:40][CH2:41][CH2:42][NH:43][CH3:44].[Cl-:45].[Cl:23][c:24]1[cH:25][cH:26][c:27]([C:30](=[O:31])[NH2:32])[n:28][cH:29]1.[Cl:49][CH2:50][Cl:51].[Cs+:37].[Cs+:38].[Cu:47][I:48].[NH4+:46].[O:52]1[CH2:53][CH2:54][O:55][CH2:56][CH2:57]1>>[c:2]1([NH:32][C:30]([c:27]2[cH:26][cH:25][c:24]([Cl:23])[cH:29][n:28]2)=[O:31])[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([O:21][CH3:22])[cH:13][c:14]1[C:15]21[N:16]=[C:17]([NH2:20])[O:18][CH2:19]1Participants
11
Reactant 10
HCID 223Ammonium
HCID 312Chloride
HCID 6344Dichloromethane
HCID 8070N,N'-Dimethylethylenediamine
HCID 19660Carbonate Ion
HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)
HCID 312751,4-Dioxane
HCID 104967Cesium cation2×
HCID 218831585-Chloropyridine-2-carboxamide
HCID 584661972'-Bromo-7'-methoxyspiro[1,3-oxazole-4,9'-xanthen]-2-amineProduct 1
Sources & evidence
- ORD record
- ord-926b03097c2c4549af848828c874c81a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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