Dichloromethane → 1-(tert-Butyl) 3-ethyl 4-(((trifluoromethyl)sulfonyl)oxy)-5,6-dihydropyridine-1,3(2H)-dicarboxylate

HRID 818979Notes

Reaction equation

HRID 818979 reaction equation
[CH2:44]([Cl:45])[Cl:46].[CH:35]([N:36]([CH2:37][CH3:38])[CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[F:1][C:2]([F:3])([F:4])[S:5](=[O:6])(=[O:7])[O:8][S:9]([C:10]([F:11])([F:12])[F:13])(=[O:14])=[O:15].[O:16]=[C:17]1[CH:18]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]1>>[F:1][C:2]([F:3])([F:4])[S:5](=[O:6])(=[O:7])[O:8][C:17]1=[C:18]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 67749Trifluoromethanesulfonic anhydrideHCID 81531DiisopropylethylamineHCID 64208761-(1,1-Dimethylethyl) 3-ethyl 4-oxo-1,3-piperidinedicarboxylate

Product 1

HCID 222284091-(tert-Butyl) 3-ethyl 4-(((trifluoromethyl)sulfonyl)oxy)-5,6-dihydropyridine-1,3(2H)-dicarboxylate

Sources & evidence

ORD record
ord-5c24c71b3093463c9aaa43f4d82985ad
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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