Acetone → 2,2-dimethyl-6-cyano-3,4-dihydro-2H-1,3-benzoxazin-4-one

HRID 818984Notes

Reaction equation

HRID 818984 reaction equation
[C:27]([c:28]1[cH:29][cH:30][c:31]([OH:32])[c:33]([C:35]([NH2:36])=[O:37])[cH:34]1)#[N:38].[CH3:12][C:13]1([CH3:26])[O:14][c:15]2[c:16]([cH:20][c:21]([C:24]#[N:25])[cH:22][cH:23]2)[C:17]([Cl:19])=[N:18]1.[CH3:44][C:45](=[O:46])[CH3:47].[H-:9].[N:10]#[N:11].[Na+:8].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[nH:1]1[cH:2][cH:3][cH:4][cH:5][c:6]1=[O:7]>>[O:7]=[C:17]1[c:16]2[c:15]([cH:23][cH:22][c:21]([C:24]#[N:25])[cH:20]2)[O:14][C:13]([CH3:12])([CH3:26])[NH:18]1

Participants

9

Reactant 8

HCID 180AcetoneHCID 923Sodium ionHCID 947NitrogenHCID 6228DimethylformamideHCID 88712-PyridoneHCID 166653HydrideHCID 147215875-Cyano-2-hydroxybenzamideHCID 147215882,2-dimethyl-4-chloro-6-cyano-2H-1,3-benzoxazine

Product 1

HCID 108219722,2-dimethyl-6-cyano-3,4-dihydro-2H-1,3-benzoxazin-4-one

Sources & evidence

ORD record
ord-8fe9ef30d0454030af54ef0b260db9f4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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