HRID818987

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID923

Sodium ion

Na+

HCID961

Hydroxide

HO-

HCID962

Water

H2O

HCID6228

Dimethylformamide

C3H7NO

HCID7972

4-Methylmorpholine

C5H11NO

HCID10868

Dicyclohexylcarbodiimide

C13H22N2

HCID75771

1-Hydroxybenzotriazole

C6H5N3O

HCID15389443

3-(Piperidin-3-yl)-1H-indole

C13H16N2

HCID19906651

未命名化合物

HCID57438287

未命名化合物

PRODUCTS

产物

HCID9956718

2-(4-dimethylamino-4-phenylcyclohexylidene)-1-[3-(1H-indol-3-yl)piperidine-1-yl]-ethanone

C29H35N3O

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-388f955d128148609f731ea741e13258
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[CH3:26][N:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1.[CH3:33][N:34]([C:35]1([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[CH2:36][CH2:37][C:38](=[CH:41][C:42](=[O:43])[OH:44])[CH2:39][CH2:40]1)[CH3:51].[CH3:85][N:86]([CH3:87])[CH:88]=[O:89].[CH:52]1([N:53]=[C:54]=[N:55][CH:56]2[CH2:57][CH2:58][CH2:59][CH2:60][CH2:61]2)[CH2:62][CH2:63][CH2:64][CH2:65][CH2:66]1.[CH:67]1([N:68]([CH:69]2[CH2:70][CH2:71][CH2:72][CH2:73][CH2:74]2)[C:75]([NH2:76])=[O:77])[CH2:78][CH2:79][CH2:80][CH2:81][CH2:82]1.[NH:11]1[CH2:12][CH:13]([c:17]2[cH:18][nH:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]23)[CH2:14][CH2:15][CH2:16]1.[Na+:84].[OH-:83].[OH2:90].[OH:1][n:2]1[c:3]2[cH:4][cH:5][cH:6][cH:7][c:8]2[n:9][n:10]1>>[N:11]1([C:42]([CH:41]=[C:38]2[CH2:37][CH2:36][C:35]([N:34]([CH3:33])[CH3:51])([c:45]3[cH:46][cH:47][cH:48][cH:49][cH:50]3)[CH2:40][CH2:39]2)=[O:43])[CH2:12][CH:13]([c:17]2[cH:18][nH:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]23)[CH2:14][CH2:15][CH2:16]1